Harm.

harm
noun
1. physical injury or mental damage; hurt: to do him bodily harm
2. moral injury; evil; wrong
verb (used with object)
3. to do or cause harm to; injure; damage; hurt: to harm one's reputation

self-de.struct
verb (used without object)
1. to destroy itself or oneself: The missile is built so that a malfunction will cause it to self-destruct
2. to cause itself or oneself to reach a state of collapse, dysfunction, confusion, or the like: The committee is so disorganised it will probably self-destruct before it can accomplish anything

Self harm and self-destruction come in some many different forms.  Drugs.  Alcohol.  Smoking.  Sexual Philanthropy.  Mutliation.  Gossip.  Mistakes.  Fear.  Narcissism. 

grow some balls and say it too my face.